Hooker Beck Cutting will start alongside teammate Nick Rigby, who is named at tighthead prop, while James Scott and Nick David are named amongst the replacements. The game will be shown live on the S4C Facebook page.
The side opened the U19 International Series with a 24-8 victory over France on 11 August in Stellenbosch.
England Under 18s Coach Peter Walton said: “It was always the plan to give everyone as much game time as we can, so we want to give every player a start out here as it’s a development tour.
“Wales is always a game full of physicality. We played them earlier in the year and know we need to up our game from that performance.
“I want us to go out there and play with passion, creativity and perform as I know we can do.
“We have had a good few days since we played France. We went out on safari which gave the lads a chance to connect off the pitch.
“It was great to see what South Africa has to offer outside of a rugby environment and that’s important for the players.
“They loved it, and had loads of fun. The camaraderie was great to see and that’s another reason why we come out here.
“It’s not all about rugby – we challenge them off the pitch and that helps develop them. They are really coming together on and off the pitch.”
England Under 18s team
15 Ollie Hassell-Collins (London Irish, St Paul’s School)
14 Tom Seabrook (Gloucester Rugby, Dean Close School)
13 Cadan Murley (Harlequins, Bishop Wordsworth’s School)
12 Cameron Redpath (Sale Sharks, Sedbergh School)
11 Tom de Glanville (Bath Rugby, Beechen Cliff School)
10 Kieran Wilkinson (Sale Sharks, Kirkham Grammar School)
9 Ollie Fox (Yorkshire Carnegie , New College Pontefract)
1 George Head (Harlequins, Tonbridge School)
2 Beck Cutting (Worcester Warriors, Bromsgrove School)
3 Nick Rigby (Worcester Warriors, Warwick School)
4 Josh Basham London Irish, Wellington College)
5 Alex Coles Northampton Saints, The Perse School)
6 Richard Capstick (Exeter Chiefs, Exeter College)
7 Aaron Hinkley (Gloucester Rugby, St Peter’s High School)
8 Tom Willis (C) (Wasps, The Henley College)
Replacements
16 Tom Rowland (Bristol Rugby, Bristol Grammar School)
17 Will Capon (Bristol Rugby, Bristol Grammar School)
18 Joe Heyes (Leicester Tigers, Wyggeston & QEI College)
19 James Scott (Worcester Warriors, Malvern College)
20 Sam Moore (Sale Sharks, Sedbergh School)
21 Will Porter (Wasps, Merchant Taylors’ School)
22 Sam Spink (Wasps, Wellington College)
23 Nick David (Worcester Warriors, Warwick School)
Fixtures
• Friday 11 August | England U18 24-8 France | Paul Roos Gymnasium, Stellenbosch
• Tuesday 15 August | England U18 vs Wales | Paarl Gymnasium, Paarl (kick-off 1.15pm BST)
• Saturday 19 August | England U18 vs SA Schools | City Park, Athlone (kick-off 1pm BST)