Warriors will host Leinster A in the semi-finals of the B&I Cup at Sixways on the weekend of March 13-15.
Warriors will be looking to prevent Leinster A from retaining the trophy for a third consecutive year after the Irish side beat Rotherham Titans 51-32 at Clifton Lane last month.
Their passage through to the semi-finals came amongst a bumper weekend for the Dublin side, who also progressed through to the knockout stages of the European Champions Cup.
Warriors have won every match on their way to the semi-finals so far after defeating Moseley, Munster A and Nottingham twice each in the pool stages, before ousting Pontypridd 24-10 last month in the quarters.
And if they can overcome the challenge of the reigning champions, they will face a trip in the final to either Doncaster Knights or Bristol Rugby who contest the other semi-final.
Confirmation of the date of the game as well as ticket information will be available later this week.
B&I Cup semi-finals, March 13-15
Game 1: Doncaster Knights v Bristol
Game 2: Worcester Warriors v Leinster A
The final will be held at the home of the winner of Game 1 on April 3-5.