Warriors will hand debuts to trialist Wilhelm van der Sluys and Academy youngster Afeafe Haisila Lokotui when they travel to the Ricoh Arena to face Wasps in the Anglo-Welsh Cup this Sunday (kick-off 3pm).
Van der Sluys, who joined the Club earlier this week, is straight into the second row while Haisila Lokotui will make his bow on the wing.
Meanwhile, Sam Lewis makes his long-awaited return from injury having not featured since scoring a hat-trick against London Scottish in the Championship semi-final second leg in May 2015.
Sam Betty also returns to the back row alongside Lewis and Matt Cox.
Tom Biggs makes his comeback on the wing, while Josh Adams moves to full-back following his impressive two-try showing last weekend against Bristol Rugby.
Tom Heathcote skippers the side at fly-half with Max Stelling and Andy Short in the centre, while Michael Dowsett keeps his place at scrum-half following his try on debut last Friday.
In the pack, Derrick Appiah makes his first start for the Club in a front row with Jack Singleton and Mike Daniels. Andrew Kitchener partners Van der Sluys in the second row.
Warriors Under 18 youngster Alex Hearle, who studies at Shrewsbury Sixth Form College, could make his Club bow from the bench.
Warriors
15 Josh Adams
14 Afeafe Haisila Lokotui
13 Andy Short
12 Max Stelling
11 Tom Biggs
10 Tom Heathcote (C)
9 Michael Dowsett
1 Derrick Appiah
2 Jack Singleton
3 Mike Daniels
4 Andrew Kitchener
5 Wilhelm van der Sluys
6 Sam Betty
7 Sam Lewis
8 Matt Cox
Replacements
16 Matti Williams
17 Ryan Bower
18 Biyi Alo
19 Justin Clegg
20 Sam Ripper-Smith
21 Huw Taylor
22 George de Cothi
23 Alex Hearle