Warriors centre Ben Te’o will start for England on Saturday as they take on France in the NatWest 6 Nations in Paris (kick-off 4.45pm GMT).
Te’o will start at outside centre to make his 12th England appearance, with Elliot Daly (Wasps) returning to the starting XV at left wing. Anthony Watson (Bath Rugby) moves from right wing to full-back with Jonny May (Leicester Tigers) switching wings.
Injury has ruled out captain Dylan Hartley (Northampton Saints) so Jamie George (Saracens) will replace him at hooker in what is an otherwise unchanged starting forward pack to the one that faced Scotland last month.
Owen Farrell (Saracens) will captain the team with Mako Vunipola (Saracens) named as vice-captain.
There are six changes among the eight finishers including Luke Cowan-Dickie (Exeter Chiefs), Mike Brown (Harlequins), James Haskell (Wasps), Jonathan Joseph (Bath Rugby), Sam Simmonds (Exeter Chiefs) and Kyle Sinckler (Harlequins).
Head Coach Eddie Jones said: “This game is about the opportunity for the team to move forward and we want a response from the players this week. Against France we want to be brutal and aggressive on the gainline and to play with a great tactical discipline.”
England
15 Anthony Watson (Bath Rugby 31 caps)
14 Jonny May (Leicester Tigers 32 caps)
13 Ben Te’o (Worcester Warriors 11 caps)
12 Owen Farrell (C) (Saracens 56 caps)
11 Elliot Daly (Wasps 16 caps)
10 George Ford (Leicester Tigers 43 caps)
9 Danny Care (Harlequins 79 caps)
1 Mako Vunipola (Saracens 47 caps) (VC)
2 Jamie George (Saracens 23 caps)
3 Dan Cole (Leicester Tigers 80 caps)
4 Joe Launchbury (Wasps 50 caps)
5 Maro Itoje (Saracens 17 caps)
6 Courtney Lawes (Northampton Saints 64 caps)
7 Chris Robshaw (Harlequins 62 caps)
8 Nathan Hughes (Wasps 13 caps)
Replacements
16 Luke Cowan-Dickie (Exeter Chiefs 4 caps)
17 Joe Marler (Harlequins 54 caps)
18 Kyle Sinckler (Harlequins 8 caps)
19 James Haskell (Wasps 75 caps)
20 Sam Simmonds (Exeter Chiefs 5 caps)
21 Richard Wigglesworth (Saracens 29 caps)
22 Jonathan Joseph (Bath Rugby 38 caps)
23 Mike Brown (Harlequins 67 caps)